Does Ivermectin Reduce Fertility in Males? Opinions right now are based more on “conspiracy theory” than science. While I use theory quite a bit, I prefer data. If there is inadaquate data, as there is now, you are left with theory alone. Under the theory that “Pharma is Evil” and does nothing for a good reason, something we all agree on, you can reach two very different conclusions about whether or not Ivermectin reduces fertility.
So let’s look at both sides of the argument on motivation of reporting adverse events allegedly associated with Ivermectin.
First, that Ivermectin does reduce fertility in males. Merck is the oldest and most evil of all pharmaceutical companies. On that basis, you can argue that Merck and related Globalist organizations were trying to reduce breeding rates in Africa. We’ll get to the studies on that later.
There’s a history of Globalist efforts to reduce Onchocerciasis in Africa that predates Ivermectin which I think is a relevant background to this debate. Let’s look at the Onchocerciasis Control Program which began before Merck’s Ivermectin program.
The Onchocerciasis Control Program (OCP) of the World Bank Group began in 1974.
Robert McNamara led the program for World Bank Group. Most people know McNamara’s name. From January 21, 1961 – February 29, 1968, Robert McNamara was Secretary of Defense for the United States. McNamara infamously sprayed US soldiers and the Vietnamese people with DDT during his tenure as SecDef.
In 1968, McNamara resigned as Secretary of Defense to become President of the World Bank. McNamara became President of the World Bank Group in April 1, 1968 and remained President until June 30, 1981.
In April 1972, McNamara coordinated the involvement of UN Agencies at the World Health Organization (WHO), the Food and Agriculture Organization (FAO, and United Nations Development Programme (UNDP) “to propose a multi-donor international effort to control river blindness.”
“The focus of the program was aerial insecticide spraying to kill the larvae of the black fly.” Pictured below: A helicopter used in the Onchocerciasis Control Program.
Areas sprayed:
Review of the National Program for Onchocerciasis Control in the Democratic Republic of the Congo
For 14 years, OCP operations were based exclusively on the spreading of insecticides by helicopters and aircraft over the breeding sites of black flies in order to kill their larvae. The announcement of the donation of Mectizan® (ivermectin) by Merck & Co. Inc. in 1987 made it possible in 1989 to add ivermectin treatment to exclusive vector control by larvicides.
Merck has since given away over 4 billion free doses of Ivermectin (Mectizan) throughout Africa.
Merck: 35 Years: The Mectizan® Donation Program, 2022
Today, the MDP is the longest-running, disease-specific drug donation program of its kind and has been influential in the development of a number of other drug donation programs. And, the MDP’s community-directed strategy used to distribute Mectizan has enabled add-on health services to be introduced in remote communities where health services are limited. The program reaches more than 300 million people in the affected areas annually, with more than 4.4 billion treatments donated since 1987.
People in the communities are an integral part of the distribution process in 49 countries where Mectizan has been distributed.
River Blindness is a disease caused by the nematode parasite Onchocerca volvulus. Black flies feed upon hosts infected Onchocerca volvulus and transfer the parasite to others. Once a person is infected, the parasite migrates to internal tissues of the eye, causing inflammation, bleeding and other complications that lead to blindness. Ivermectin kills the parasite in it’s larval stage.
Ivermectin was discovered as part of a research project by Merck. Satoshi Ōmura collected bacteria from soil in Japan, screened them for their ability to kill nematodes, and sent his sample of Streptomyce avermectinius to Merck. William Campbell of Merck isolated 8 excretions of the bacteria, named avermectins, and selected two of the best, which he used in an 80/20% ratio in what came to be known as Ivermectin.
In 1971, Ōmura took a sabbatical in the laboratory of Max Tishler (1906–1989), an eminent professor of chemistry at Wesleyan University in Connecticut. A year earlier, Tishler had retired from an illustrious research career at the pharmaceutical company Merck. Before returning to Japan in 1973, Ōmura arranged a pioneering agreement between the company and the research institute. Kitasato would continue to collect samples and screen them, and then send the most promising ones to Merck Research Laboratories in Rahway, New Jersey, for testing and development. The institute would receive royalties from any products that were commercialized through the partnership.
To test potential treatments, the Merck researchers first infected mice with nematodes and then fed each mouse a different culture sample supplied by Ōmura’s team. They found that one culture was extraordinarily effective at ridding mice of worm infestations. This culture was derived from soil collected near a golf course in Kawana, about 80 miles southwest of Tokyo. Ōmura identified the bacterium in that culture as a new strain, which was ultimately christened Streptomyces avermectinius.
Pictured: Satoshi Ōmura collecting soil from the very site where the fateful sample containing Streptomyces avermectinius (S. avermitilis) was taken in 1973
The Ivermectin donation program for Onchocerciasis is widely considered to be a roaring success. A sculpture of a child leading a blind man with a stick- “Sightless among Miracles,” is at the World Health Organization, the World Bank, Merck’s Headquarters in New Jersey, and at Jimmy Carter’s museum in Atlanta. Vaccinologist Peter Hotez is a big fan, by the way. Also pictured is Robert McNamara with the sculpture.
Below is the photo on which the River Blindness statue is based on, where children often have to lead blind adults around. This is something that Robert McNamara noticed on a tour of Africa as President of the World Bank.
Below is a video from the World Bank commemorating Robert McNamara’s role and the history of the Statue going back to 1972, (although McNamara stepped down in 1981, and Merck’s Mectizan program did not begin until 1987).
Under the theory that the World Bank is also evil, it’s easy to believe that they would promote Ivermectin because it reduced fertility.
On the other hand, one can argue that Ivermectin is being attacked now because it is likely beneficial in treating cancer. I have written about this potential several times. Merck and the other evil pharmaceutical companies are now developing mRNA cancer “vaccines” to cure the “turbo” cancer that pharmaceutical companies created with mRNA vaccines in the first place.
So what’s the truth? You can argue motiviations either way based on the fact that “pharma is evil.” That leaves Science to settle the question. And as always, that’s the most difficult question, because modern Science is largely a Cult of Quacks and Pharma Shills with some truth mixed in. The last people in the world that you can trust to answer the question are the FDA and Pharma. So that leaves us to figure out the truth somehow. It’s a ridiculously simple question, and an important one.
Here’s the evidence that Ivermectin reduces male ferlitily. There are three main studies that I have found. One was on sheep in Turkey in 2002; another in Nigeria in 2011 on humans; another was in rats in 2018.
An Investigation of the Effects of Ivermectin on Blood Serum, Semen Hyaluronidase Activities and Spermatological Characteristics in Sheep, Sadettin Tanyildizi and Tanzer Bozkurt, 2002.
After subcutaneous injections of Ivermectin, the authors found that Ivermectin decreased sperm concentrations and sperm motility and they recommended using not using Ivermectin while trying to breed sheep.
No differences were observed of abnormal spermatozoa rates when compared with the control group. Furthermore, there was no correlation between hyaluronidase activities of serum or semen with sperm characteristics. These findings indicate that ivermectin increases hyaluronidase activity of serum and semen in sheep, but it decreases sperm motility and concentrations. In conclusion, the use of ivermectin is not suitable during ramming season and in rams used for breeding due to the deleterious effects on fertility.
Effects of Ivermectin therapy on the sperm functions of Nigerian onchocerciasis patients, Idonije O.Ba ., Asika E.Cb ., Okhiai, Oc and Nweke I.Nd, 2011.
Sperm counts and sperm motility decreased in all of the 37 subjects after taking Ivermectin. Sperm morphology increased.
it is evident that ivermectin therapy has significant adverse effects on the sperm functions of male onchocerciasis patients so treated. There was a significant reduction or drop in the sperm counts of the patients after their treatment with ivermectin. Furthermore, the study showed a significant and remarkable drop in the sperm motility of the patients after their treatment with ivermectin. As for the morphology of the sperm, there was a rise in the abnormal sperms after treatment compared with the morphology before the commencement of treatment. These changes no doubt are as results of the effects of the drug on the sperm function of the patients.
Effects of ivermectin and its combination with alpha lipoic acid on expression of IGFBP-3 and HSPA1 genes and male rat fertility, Z K El-Maddawy 1, W S H Abd El Naby 2 2018
The authors of this study have unfortunately hidden their full text behind a paywall. It’s difficult to get a read on this study. They “injected” rats with Ivermectin, which seems a bit extreme. It doesn’t say where they injected them either, which is certainly a relevant question given their results.
They say Ivermectin injections in rats decreased testosterone levels, lowered sperm count, lowered motility, lowered weight of reproductive organs (yikes). But again, where did they inject them?
This study was conducted to evaluate the effects of ivermectin (IVM) with therapeutic dose (injected with 0.56 mg/kg b.wt.) either alone or combined with alpha lipoic acid (ALA) (50 mg/kg b.wt daily) on expression of testicular insulin-like growth factor binding protein-3 (IGFBP-3) and heat-shock protein A1 (HSPA1)) genes in the testes, as well as on male rat fertility parameters. Results revealed that expression levels of IGFBP-3 and HSPA1 were significantly increased in testis of the IVM-treated group relative to the control group. Furthermore, injection of ivermectin showed a significant decrease in serum testosterone level, sperm count, motility %, live sperm% and index weight of reproductive organs, and a significant increase in sperm abnormalities. Moreover, IVM induced oxidative stress and pathological alterations in the testes. Meanwhile, the administration of ALA with IVM prevented testicular damage and improved all previous parameters. We concluded that ivermectin has undesirable effects on male fertility and altered expression of IGFBP-3 and HSPA1 genes in the testes, while the administration of alpha lipoic acid can ameliorate the adverse effects of ivermectin.
CONCLUSION
Does Ivermectin lower fertility in males? I don’t know. The evidence is too much to dismiss in my opinion. It’s a relatively simple question to answer with “before and after” studies.
If you’re buying Petmectin from this guy, consider having your sperm counts checked before and after taking it, and report the results. Even if these concerns are proven to be trut, they may or may not be enough for you to change your decision about what anti-cancer treatments to pursue, but your decision should be based on the best information available.
Ivermectin does very likely have anti-cancer effects, but any adverse events should be known and disclosed. Fenbendazole is another example. After I wrote Much of what we call Cancer appears to be a Symbiotic Relationship between Bacteria and diseased cells which can be cured with Ivermectin, Lactoferrin, Fenbendazole and so on, Dr. Huber raised concerns about liver enzymes, so I published Dr. Huber has concerns about liver toxicity and quality of Fenbendazole.
I’m not trying to be smart here. I’m not trying to deduce the truth from conspiracy theory. I’d just like to know the answer. I don’t want to debate motivation theory. I don’t want to talk about NASA’s fake moon landing. Just get the data on sperm counts, sperm motility, and sperm morphology before and after taking Ivermectin. If we had properly functioning regulatory agencies, we’d already know the answer. But since we don’t, it’s on us to get the data.
Charles Wright
Another point, I wanted to look up if Merck was conducting any fertility studies in the 60s and 70s, but Google wouldn't let me limit search results by date. "This function is not currently available." They are sure doing a lot of it in recent years.
So many conspiracy theories are now truth. But you hit the issue spot on. Saying there’s not enough evidence either way is fair and good enough because that’s just the way it is. One can still weigh risks and benefits.